2 edition of Modulation of baroreceptor reflex by three endogenous neuropeptides in the rat found in the catalog.
Modulation of baroreceptor reflex by three endogenous neuropeptides in the rat
Julie Yu-Hwa Chan
Written in English
|Statement||by Julie Yu-Hwa Chan.|
|The Physical Object|
|Pagination||xiii, 239 leaves, bound :|
|Number of Pages||239|
The baroreflex or baroreceptor reflex is one of the body's homeostatic mechanisms that helps to maintain blood pressure at nearly constant levels. The baroreflex provides a rapid negative feedback loop in which an elevated blood pressure reflexively causes the heart rate to decrease and also causes blood pressure to decrease. Decreased blood pressure decreases baroreflex activation and causes. Human muscle sympathetic activity (MSA) is modulated by arterial baroreflex mechanisms: the sympathetic impulses are grouped in pulse synchronous bursts occurring preferentially during transient reductions of blood pressure (Delius et al. ), and changes in arterial baroreceptor firing induce reciprocal changes in the strength of the MSA (Wallin et al. ; Wallin & Eckberg, ).
Opioid modulation of baroreceptor reflex sensitivity in dogs. Szilagyi JE. Opioid peptides can modulate cardiovascular function both directly and by modifying specific responses. The action of opioids on baroreceptors was evaluated in anesthetized dogs. Baroreceptor responsiveness was determined by observing the peak heart rate and blood Cited by: Start studying Adrenergic Agonist. Learn vocabulary, terms, and more with flashcards, games, and other study tools.
What is the baroreceptor reflex? The baroreceptor reflex or baroreflex is the body's way of responding to a change in blood pressure. Baroreceptors in the arteries notice that something has changed. When they sense a change in pressure, they send out signals through nerves to a part of the brain called the brainstem. The increase in pressure causes more signals to be sent to the brainstem. A good example of the importance of the baroreceptor reflex in normal physiology is its activation whenever a person goes from a lying to a standing position. When a person goes from a lying to a standing position, there is a shift of to ml of blood from the veins of the thoracic cavity to veins in the lower extremities, which expand to.
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To investigate modulation of the aortic baroreceptor reflex by neuropeptides, we microinjected these neuropeptides into the medial area of the rat NTS and examined their effects on the depressor and bradycardic responses to electrical stimulation of the aortic nerve which contains mainly baroreceptor afferent fibers in by: Regulatory Peptides, 28 () 23 Elsevier REGPEP Tonic suppression of baroreceptor reflex by endogenous neurotensin in the rat Chiung-Tong Chen 1, Julie Y.H.
Chan ~,2, Charles D. Barnes2 and Samuel H.H. Chan. ~ Depanment and Institute of Pharmacology, National Yang-Ming Medical College, Taipei, Taiwan (Republic of China) and 2Department of Veterinary and Comparative Cited by: The baroreceptor reflex gain upon volume loading was also low in anaesthetized α 2A ‐KO mice.
The reflex tachycardia evoked by intravenous sodium nitroprusside injection was also significantly less in α 2A ‐KO mice as compared to WT, conscious as well as anaesthetized; the baroreceptor reflex gains were decreased by 50 and 65%, by: Modulation of baroreceptor reflex (BRR) by endogenous substance P (SP) in the brain was investigated in rats anesthetized with pentobarbital sodium.
Intracerebroventricular administration of the undecapeptide (15 or 30 nmol) and its antagonist, (d -Pro 2, d -Trp 7,9)-SP (30 or 60 nmol) or SP antiserum (1: 20), respectively, promoted a significant increase and decrease in the sensitivity of Cited by: Tonic suppression of baroreceptor reflex response by endogenous neuropeptide Y at the nucleus tractus solitarius of the rat Neurosci.
76 () 10 Kubo, T. and Kihara, M., Modulation of the aortic baroreceptor reflex by neuropeptide Y, neurotensin and vasopressin microin- jected into the nucleus tractus solitarii of the rat Cited by: The baroreceptor reflex is a key blood pressure regulatory mechanism. This chapter provides an overview of recent advances focusing on novel experimental approaches and mechanisms that determine baroreflex sensitivity.
Gene discovery and technological advances now enable molecular mechanisms essential to baroreflex function to be by: Cowley AW Jr, Monos E, Guyton AC () Interaction of vasopressin and the baroreceptor reflex system in the regulation of arterial blood pressure in the dog.
Circ Res – Google Scholar Cited by: 6. The contribution of exogenous and endogenous opioid peptides to the central modulation of the baroreceptor reflex was investigated in rabbits. Baroreceptor sensitivity was assessed in pentobarbitone anaesthetised animals by measuring heart period in response to rises in arterial pressure after bolus intravenous injections of phenylephrine and falls induced by intravenous Cited by: Reflex Mechanisms for Maintaining Normal Arterial Pressure.
Baroreceptor reflex. It is the baroreceptor arterial pressure control system and it is the. best known nervous mechanism. for control of arterial pressure. Basically, this reflex is initiated by stretch receptors, called either. baroreceptors. pressoreceptors.
Start studying Baroreceptor Reflex. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Introduction. While it is generally believed that glutamate is the primary neurotransmitter released by baroreceptor projections to second order neurons in the nucleus tractus solitarius (NTS) (Meeley et al., ; Pawloski-Dahm and Gordon, ; Andresen and Yang, ), the presence of neuropeptides including substance P (SP) at all levels of the baroreflex arc suggest that this peptide Cited by: Morphine-like compounds are known to facilitate the baroreceptor reflex at the level of the nucleus tractus solitarii (2).
It has also been reported that endogenous opioid peptides might be related to the altered baroreflex function in hypertensive animals (3,4).Author: Mitsuhiro Yoshioka, Masahiro Tochihara, Hiroko Togashi, Hideya Saito. Other articles where Baroreceptor reflex is discussed: human nervous system: Reflex pathways: trigger what is called the baroreceptor reflex, which causes a decrease in the discharge of sympathetic vasomotor and cardiac outflows whenever an increase in blood pressure occurs.
In addition, the baroreceptor reflex causes stimulation of vagal cardioinhibitory neurons, which produces a. The structure, connections, and function are explained in exquisite detail, making this an essential book for any graduate student or scientist working on the rat or mouse nervous system.
Show less The previous editions of The Rat Nervous System were indispensable guides for those working on the rat and mouse as experimental models. These results provide evidence that endogenous catecholamines in the rat NTS are involved in alpha 2 adrenoceptor-mediated modulation of the aortic baroreceptor reflex.
View Show abstract. Differential modulation of synaptic transmission by neuropeptide Y in rat neocortical neurons. leading to the proposal that it is an endogenous antiepileptic agent.
In the neocortex, where NPY. Interaction of baroreceptor and chemoreceptor reflexes. Modulation of the chemoreceptor reflex by changes in baroreceptor activity. Heistad DD, Abboud FM, Mark AL, Schmid PG.
The purpose of this study was to determine whether the level of arterial pressure and degree of baroreceptor activation affect responses to stimulation of by: The baroreceptor reflex dampens the short-term fluctuations in blood pressure by feedback modulation of heart rate (HR) and vascular resistance.
Impairment of this reflex has been observed in. These theoretical considerations have been applied to the arterial baroreceptor reflex and various models predicting the arterial pressure Mayer waves have been proposed (Madwed et al. ; Burgess et al. However, the existence of a resonance frequency in the arterial baroreceptor reflex has never been proven by: The purpose of this review is to delineate the general features of endocrine regulation of the baroreceptor reflex, as well as specific contributions during pregnancy.
Gai n o f th e baroreceptor-hear t rat e refle x wa s calculate d a s th e chang e i n heai 4 Baroreceptor-heart rate reflex in a lizard 19 9 perio d induce d b y a uni t chang e i n mea n systemi.
Participation of endogenous neuropeptide Y in the suppression of baroreceptor reflex response by locus coeruleus in the rat. Chan JY(1), Shih CD, Chan SH.
Author information: (1)Department of Medical Research, Veterans General Hospital-Taipei, Taiwan, by: 9. Human muscle sympathetic activity (MSA) is modulated by arterial baroreflex mechanisms: the sympathetic impulses are grouped in pulse synchronous bursts occurring preferentially during transient reductions of blood pressure (Delius et al.
), and changes in arterial baroreceptor firing induce reciprocal changes in the strength of the MSA (Wallin et al. ; Wallin & Eckberg, ).Cited by: